信号传导及转录激活蛋白(signal transducer and activator of transcription),即STAT。是一种能与DNA结合的蛋白质独特家族。含有SH2和SH3结构域,可与特定的含磷酸化酪氨酸的肽段结合。当STAT被磷酸化后,发生聚合成为同源或异源二聚体形式的活化的转录激活...详情
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